XB-FEAT-22069202

vgf

This is the community wiki page for the Xenopus vgf genes. Please feel free to enter here any information relevant to these genes that is not found elsewhere on Xenbase.

nomenclature changes

16MAY2023

Xenopus gene was renamed, changing from sprr3, small proline rich protein 3 to vgf , VGF nerve growth factor inducible.

Changed XB-GENE-22069203 Xtr Gene ID: 105945420 from sprr3 to vgf as

1) NCBIi recognizes it as the ortholog of human VGF

2) supported by synteny, with conserved flanking genes serpine1 and ap1s1 upstream and nat16 (plus duplicates) downstream.

SYNTENY PATTERNS

HumanChr1: SPRR4> SPRR1A> SPRR3> LOC(ncRNA)> SPRR1B> SPRR2D< SPRR2A< SPRR2B

Note: NO Xenopus genes have been characterised as SPRR# orthologs

Synteny is conserved between Human and Xenopus

HumanCHR7: TRIM56> SERPINE1> AP1s1> VGF< NAT16< MOGAT3< PLOD3< ZNHITI> CLDN15>

Xtrop.v9.1 scff48: nat16> XB5892957(unch) > [tRNAs] vgf> ap1s1< [trnas] serpin1< LOC100495872

Xtrop.v10.Chr3: LOC116409833(muc3)> serpine1> ap1s1> vgf> [tRNAs] XB5892957(unch? nat.14)> LOC100495706(nat16.13)> LOC116409835(nat-like.12)< XB5762451(nat.11)< LOC116409834(nat-like.10)< LOC100490742(nat-like.9)< LOC100490911(nat-like.8) XB5761890(nat16.7)< LOC116409523 (nat-like.6)< LOC116409836(nat-like.5)< LOC100490569(nat.4) < LOC101730755(nat.3)< LOC100491420(nat.2)< nat16< mogat3< mogat2.1<

Xla.chr3L: serpine1.L> ap1s1.L> LOC108711739(vgf)> LOC108711740(nat16)< LOC108710379(nat)< LOC108711741(nat)< LOC108711742(nat)< LOC108710380(nat16)< LOC108710381(nat16-p)< LOC108710382(nat16p)< LOC121393059(natlike) LOC121401654(natike) < LOC121401655(lncRNA)< nat16.L< < mogat3.L< mogat2.1.L<

Xla.chr3S: serpine1.S> ap1s1.S> LOC108703510(vgf)> LOC108703511(nat16.5)< LOC108703512(nat16.4)< XB5761890.S(nat16.3)< LOC108703513(nat16.2)< LOC121402082(ncRNA)< LOC108703454(unch/nat16.1?)< LOC108703514(mblac1 like)> LOC733301(tmem4l6m5.1) LOC108703455(tmem4l6m5.2)> LOC108703456(tmem4l6m5.3)> lamtor4.S> LOC108703516(trappc14)