XB-FEAT-29090326

ovos5h

This is the Xenbase community page for Xenopus ovos5h. Please feel free to record here anything relevant to these genes/proteins that is not found elsewhere on Xenbase.

nomenclature updates

18DEC2025

Xenopus Gene Name and symbol was changed from LOC108644866, ovostatin-like to ovos5h, ovostatin 5H following phylogenetic analysis of the vertebrate ovostatin and A2M protein/gene family by Xenbase and the HGNC.

LOC108644866 is recorded as a Synonym.

OVOS protein background

Ovostatins (OVOS gene /protein family) were originally called “ovomacroglobulins”, and were first identified in the 1960's as an abundant proteins from the 'whites' of chicken eggs [1]. Ovostatins were subsequently shown to be active enzymes that inhibited the peptidases trypsin, papain and thermolysin [2].

References:

1. Miller etal 1966. Biochemistry. 1966;5:952–8.

2. Nielsen et al 1994. DNA Seq. 1994;5:111–9