XB-FEAT-5740333

linc02867

This is the community wiki page for the gene linc02867 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

nomenclature changes

12/05/2016

Human symbol has changed for genepage ID: 5740333 From loc440330 to loc105371184

10.18.2019

Human symbol has changed for Entrez Gene: 105371184. From LOC105371184 to linc02867

10.FEB.2021

Human symbol has changed for genepage ID: 5740333 From linc02867 to STUB1-DT, STUB1 divergent transcript . a psuedo gene in Humans.

XB curators decided to keep this gene name as is, unchanged, as even though it is annotated/named as a non-coding lncRNA, it appears it to be functional protein coding gene in Xenopus.

Note there is no gene in Xla.S

Do not gene change name unless further compelling evidence is presented/published.

synteny maps

07JUNE2023

Xtr: linc02867< stub1> jmjd8<. XB5729975< LOC100487504[trim25]<

Xla.L LOC108701691[trim25] jmjd8.L> stub1.L> loc440330.L(gene30787) rhbdl1.L<

Xla.S XB5729975> stub1.S< rhbdl1.S< (note: not present in S)

Human: ROT2> LOC#> RHBDL1> STUB-DT<. STUB1> JMJD8<. WDR24<

Notes: Although Human STUB-DT1 and the Xenopus linc02867/loc440330 are both flanked by STUVB1 and RHBDL1, these are not the same/orthologous genes.

NCBI also doesnt identify eitehr Xenopus gene as orthols of STUB_DT1- mentioning on 3 orthog ( in hedgehog opossuma nd green anole).

XB has therefore remove the human STUB-DT1 [Gene ID: 105371184] from this gene page.

DIOPT orthology group anlaysis

Using the below seq, DIOPT/EggNog tool matches this protein with >250 proteins from 235 species, including many fish mammals, with Xenopus [8364.ENSXETP00000061708], Danio rerio [7955.ENSDARP00000066582 zgc:112496]; Xiphophorus maculatus [8083.ENSXMAP00000019006].

Unfortiunately none of the close homologs are named in an informative manner, and no functional annotations are retrieved.
Its a mystery!. 

Xtrop.linc02867 Entrez Gene: 100145131

>NP_001120112.1 uncharacterized protein LOC100145131 [Xenopus tropicalis] MAQNSGLFHSEDPAVWQKASDIYWDVIAAKGAKQKKLVSLDKWFQEELPPCIAARPHKHLTREELVKLME WKLTRGKFRPRLQQLVASNPDGAVETCTEKAFKLLPEVSAAINELCQLKGIGPATASAVLAAGAPELTAF MADEAVESIPGLTPVQYTLKHYLRYLEELRKKAAALSTEGSSEKWTPHQVELCLWAWEVARKLCPNLLGS QESGKIEERPKKKLKTK