XB-FEAT-5847664

lipi

This is the community wiki page for the gene lip please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.

nomenclature ipdates

14MAY2026

Xenopus gene name was updated from lipase, member I to lipase I.

summary for human LIPI from NCBI

The protein encoded by this gene is a phospholipase that hydrolyzes phosphatidic acid to produce lysophosphatidic acid. Defects in this gene are a cause of susceptibility to familial hypertrigliceridemia. This gene is also expressed at high levels in Ewing family tumor cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]