XB-FEAT-6259002

mig30

This is the community wiki page for the gene mig30 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.

synteny patterns for Chr1/1L/1S

Xla v10 Chr1S aup1.S< LOC#466(il12b-like)> LOC121399253(mmp21-like)< LOC108706464(tlx3)< mig30.S< pcgf1.S>

Xla v10 Chr1L:

dqx1.L> LOC108704874(mmp21-like)> LOC108704860(TLX3) mig30.L< pcgf1.L>

Xtropicalis v10 Chr1: aup1< dqx1> LOC8405(unch)> LOC#3914(il12b-like)> LOC#3912(mmp21-like) tlx2< LOC#8406(rhobtb2-like)> wdr54< c20rf81> rdh11> LOC#8408(unch< nop56>)

Notes

1) no Xtrop mig30 gene annotated in v10 genome

2) mig30.S and mig30.L are isolated/'orphan' names- nothing else in NCBI are called mig30. = redflag.

3)EggNog homology search (09/03/20230) had the protein for mig30 matching with high confident to KAZALD1, Kazal type serine peptidase inhibitor domain 1 proteins (functionally: insulin-like growth factor binding protein).

4) these X.laevis genes should probably be renamed. Perhaps kazald1-like, as XB has a true kazald1 gene page XB-GENEPAGE-486703 already , where all genes are all on Chr7/7L/7S.

5) mig30.L link to NCBI refSeq states:

NCBI Reference Sequence: NM_001088737.1 (click to see this obsolete version) Record removed. NM_001088737.1: This RefSeq was removed because it is a nonsense-mediated mRNA decay (NMD) candidate.

6) other RefSeq proteins for mig30.L links go to "kazal-type serine protease inhibitor domain-containing protein 1 isoform X2" [Xenopus laevis] NCBI Reference Sequence: XP_041442348.1,