XB-FEAT-972249

gprc5a

This is the community wiki page for the gene gprc5a please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.

annotation notes

14MAY2026

NCBI orthology suggest this Xenopus' gene is better named gprc5d. In human and mouse, GPRC5A & GPRC5D are adjacent, but synteny with Xenopus is conserved & supports keeping these genes as orthologs of GPRC5A.

Synteny pattern:

Xtrop: brinp3> apold1> ddx47> gprc5a> henp1< chadl> l3mbtl2> rbx1>

Xla.L: brinp3.L> apold1.L> ddx47.L> gprc5a.L> henp1.L< chadl.L> nsl1.L> l3mbtl2.L> rbx1.L>

Xla.S: brinp3.S> apold1.S> ddx47.S> gprc5a.S> .... .... rbx1.S>

Human: APOLD1> DDX47> GPRC5A> GPRC5D< HEBP1< FAM234B

Mouse:APOLD1> DDX47> GPRC5A> GPRC5D< HEBP1< FAM234B

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