XB-FEAT-940948: Difference between revisions
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=srd5a2= | =srd5a2= | ||
This is the community wiki page for the gene ''srd5a2'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase | This is the community wiki page for the gene ''srd5a2'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase | ||
=nomenclature changes= | |||
7.26.2021 | |||
''Xenopus'' name changed from "steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)" to "steroid 5 alpha-reductase 2" following human as per | |||
''Xenopus'' naming guidelines. | |||
the ''Xenopus'' gene symbol is unchanged. | |||
=summary from NCBI for human SRD5A2= | |||
This gene encodes a microsomal protein expressed at high levels in androgen-sensitive tissues such as the prostate. The encoded protein is active at acidic pH and is sensitive to the 4-azasteroid inhibitor finasteride. Deficiencies in this gene can result in male pseudohermaphroditism, specifically pseudovaginal perineoscrotal hypospadias (PPSH). [provided by RefSeq, Jul 2008] | |||
Latest revision as of 11:11, 29 July 2021
srd5a2
This is the community wiki page for the gene srd5a2 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase
nomenclature changes
7.26.2021
Xenopus name changed from "steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)" to "steroid 5 alpha-reductase 2" following human as per Xenopus naming guidelines.
the Xenopus gene symbol is unchanged.
summary from NCBI for human SRD5A2
This gene encodes a microsomal protein expressed at high levels in androgen-sensitive tissues such as the prostate. The encoded protein is active at acidic pH and is sensitive to the 4-azasteroid inhibitor finasteride. Deficiencies in this gene can result in male pseudohermaphroditism, specifically pseudovaginal perineoscrotal hypospadias (PPSH). [provided by RefSeq, Jul 2008]