XB-FEAT-29078818: Difference between revisions

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Created page with "=''ovos5a''= This is the Xenbase community page for ''Xenopus ovos5a''. Please feel free to record here anything relevant to these genes/proteins that is not found elsewhere on Xenbase. =nomenclature updates= 18DEC2025 ''Xenopus'' Gene Name and symbol was changed from ''LOC100487580 , LOC108695710 and LOC108697150, ovostatin'', to ''ovos5a, ovostatin 5A'' following phylogenetic analaysis of the vertebrate ovostatin and a2m protein/gene family by the HGNC. LOC1004875..."
 
 
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LOC100487580 , LOC108695710 , LOC108697150, are recorded as Synonyms.
LOC100487580 , LOC108695710 , LOC108697150, are recorded as Synonyms.
=OVOS protein background=
Ovostatins (OVOS gene /protein family) were originally called “ovomacroglobulins”, and were first identified in the 1960's as an abundant proteins from the 'whites' of chicken eggs [1]. Ovostatins were subsequently shown to be active enzymes that inhibited the peptidases trypsin, papain and thermolysin [2].
References:
1. Miller et al 1966.  Biochemistry. 1966;5:952–8.
2. Nielsen et al 1994. DNA Seq. 1994;5:111–9

Latest revision as of 17:45, 19 December 2025

ovos5a

This is the Xenbase community page for Xenopus ovos5a. Please feel free to record here anything relevant to these genes/proteins that is not found elsewhere on Xenbase.

nomenclature updates

18DEC2025

Xenopus Gene Name and symbol was changed from LOC100487580 , LOC108695710 and LOC108697150, ovostatin, to ovos5a, ovostatin 5A following phylogenetic analaysis of the vertebrate ovostatin and a2m protein/gene family by the HGNC.

LOC100487580 , LOC108695710 , LOC108697150, are recorded as Synonyms.

OVOS protein background

Ovostatins (OVOS gene /protein family) were originally called “ovomacroglobulins”, and were first identified in the 1960's as an abundant proteins from the 'whites' of chicken eggs [1]. Ovostatins were subsequently shown to be active enzymes that inhibited the peptidases trypsin, papain and thermolysin [2].

References: 1. Miller et al 1966. Biochemistry. 1966;5:952–8. 2. Nielsen et al 1994. DNA Seq. 1994;5:111–9