XB-FEAT-485053: Difference between revisions
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= | = ''h2az1'' = | ||
This is the community wiki page for the gene '' | This is the community wiki page for the gene ''h2az1'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase. | ||
=nomenclature changes= | =nomenclature changes= | ||
08.23.2019 | 08.23.2019 | ||
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Human name has changed for Entrez Gene: 3015. From H2A histone family member Z to H2A.Z variant histone 1 | Human name has changed for Entrez Gene: 3015. From H2A histone family member Z to H2A.Z variant histone 1 | ||
=gene marker= | |||
''h2az1'' is considered a good marker for multiciliated cells. See XB-ART-59700 Lee et al 2023, PubMed ID: 37027470 | |||
=Summary from NCBI= | =Summary from NCBI= | ||
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality. [provided by RefSeq, Jul 2008] | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality. [provided by RefSeq, Jul 2008] | ||
Latest revision as of 08:35, 21 April 2023
h2az1
This is the community wiki page for the gene h2az1 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.
nomenclature changes
08.23.2019
Human symbol has changed for genepage ID: 485053 From h2afz to h2az1
Human symbol has changed for Entrez Gene: 3015. From H2AFZ to H2AZ1
Human name has changed for Entrez Gene: 3015. From H2A histone family member Z to H2A.Z variant histone 1
gene marker
h2az1 is considered a good marker for multiciliated cells. See XB-ART-59700 Lee et al 2023, PubMed ID: 37027470
Summary from NCBI
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality. [provided by RefSeq, Jul 2008]