Retinoic acid: Difference between revisions
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==Description== | ==Description== | ||
"all−trans−Retinoic acid (ATRA) is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR). The bound RAR and RXR act as transcription factors that regulate the growth and differentiation of both normal and malignant cells. Cytochromes P450 (CYPs) catalyze the 4-hydroxylation of ATRA. Retinoic acid primes embryonic stem cells to become neurons." | |||
*-Sigma Product Description | |||
[[File:RetinoicAcid.png|frame|right|Retinoic Acid structure, photo from Sigma-Aldrich]] | [[File:RetinoicAcid.png|frame|right|Retinoic Acid structure, photo from Sigma-Aldrich]] | ||
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==References== | ==References== | ||
*[https://pubchem.ncbi.nlm.nih.gov/compound/444795] | *[https://pubchem.ncbi.nlm.nih.gov/compound/444795 Pubchem] | ||
*[http://www.xenbase.org/literature/article.do?method=display&articleId=21398 Drysdale et al., 1991] | *[http://www.xenbase.org/literature/article.do?method=display&articleId=21398 Drysdale et al., 1991] | ||
*[http://www.xenbase.org/literature/article.do?method=display&articleId=50590 Nagy et al., 2015] | |||
>1484 Xenbase articles contain a reference to Retinoic Acid according to [http://www.xenbase.org/cgi-bin/textpresso/xenopus/search textpresso] | >1484 Xenbase articles contain a reference to Retinoic Acid according to [http://www.xenbase.org/cgi-bin/textpresso/xenopus/search textpresso] | ||
* | * | ||
*[[Small Molecules for Xenopus Research|Back To Small Molecules Home Page]] | *[[Small Molecules for Xenopus Research|Back To Small Molecules Home Page]] | ||
Latest revision as of 16:00, 7 March 2016
Description
"all−trans−Retinoic acid (ATRA) is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR). The bound RAR and RXR act as transcription factors that regulate the growth and differentiation of both normal and malignant cells. Cytochromes P450 (CYPs) catalyze the 4-hydroxylation of ATRA. Retinoic acid primes embryonic stem cells to become neurons."
- -Sigma Product Description
Genes Affected
Suppliers
Usage Notes
References
>1484 Xenbase articles contain a reference to Retinoic Acid according to textpresso