Retinoic acid

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"all−trans−Retinoic acid (ATRA) is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR). The bound RAR and RXR act as transcription factors that regulate the growth and differentiation of both normal and malignant cells. Cytochromes P450 (CYPs) catalyze the 4-hydroxylation of ATRA. Retinoic acid primes embryonic stem cells to become neurons."

  • -Sigma Product Description
Retinoic Acid structure, photo from Sigma-Aldrich

Genes Affected


Usage Notes


>1484 Xenbase articles contain a reference to Retinoic Acid according to textpresso