XB-FEAT-5849741: Difference between revisions
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=fmo2= | =fmo2= | ||
This is the community wiki page for the gene ''fmo2'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase | This is the community wiki page for the gene ''fmo2'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase. | ||
=nomenclature changes= | |||
05.13.19 | |||
Human name has changed for Entrez Gene: 2327. From flavin containing monooxygenase 2 to flavin containing dimethylaniline monoxygenase 2 | |||
=Summary from NCBI for human FMO2 = | |||
This gene encodes a flavin-containing monooxygenase family member. It is an NADPH-dependent enzyme that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, some human populations contain an allele (FMO2*2A) with a premature stop codon, resulting in a protein that is C-terminally-truncated, has no catalytic activity, and is likely degraded rapidly. This gene is found in a cluster with other related family members on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014] | |||
Latest revision as of 08:45, 21 May 2019
fmo2
This is the community wiki page for the gene fmo2 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.
nomenclature changes
05.13.19 Human name has changed for Entrez Gene: 2327. From flavin containing monooxygenase 2 to flavin containing dimethylaniline monoxygenase 2
Summary from NCBI for human FMO2
This gene encodes a flavin-containing monooxygenase family member. It is an NADPH-dependent enzyme that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, some human populations contain an allele (FMO2*2A) with a premature stop codon, resulting in a protein that is C-terminally-truncated, has no catalytic activity, and is likely degraded rapidly. This gene is found in a cluster with other related family members on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014]