XB-FEAT-5849741

fmo2

This is the community wiki page for the gene fmo2 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.

nomenclature changes

05.13.19 Human name has changed for Entrez Gene: 2327. From flavin containing monooxygenase 2 to flavin containing dimethylaniline monoxygenase 2

Summary from NCBI for human FMO2

This gene encodes a flavin-containing monooxygenase family member. It is an NADPH-dependent enzyme that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, some human populations contain an allele (FMO2*2A) with a premature stop codon, resulting in a protein that is C-terminally-truncated, has no catalytic activity, and is likely degraded rapidly. This gene is found in a cluster with other related family members on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014]