XB-FEAT-5751720: Difference between revisions
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Key: RSCOM-45 | Key: RSCOM-45 | ||
URL: https://ncbijira.ncbi.nlm.nih.gov/browse/RSCOM-45 | URL: https://ncbijira.ncbi.nlm.nih.gov/browse/RSCOM-45 | ||
Components: chicken, Ensembl, human, mouse, rat, vgnc, xenopus, zebrafish | Components: chicken, Ensembl, human, mouse, rat, vgnc, xenopus, zebrafish | ||
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Assignee: Elspeth Bruford | Assignee: Elspeth Bruford | ||
Hi HGNC, | Hi HGNC, | ||
I'd like your input on a PTTG1IP-like gene that is inconsistently annotated and named. | I'd like your input on a PTTG1IP-like gene that is inconsistently annotated and named. | ||
The paralogous gene, PTTG1IP, is consistently found upstream of the SUMO3 gene in Osteichthyes and | |||
The paralogous gene, '''PTTG1IP''', is consistently found '''upstream of the SUMO3''' gene in Osteichthyes and a '''PTTG1IP-like''' gene is consistently found '''upstream of the CDK14''' gene in Osteichthyes. | |||
However, in mammals this PTTG1IP-like gene is sometimes unannotated or is annotated as non-coding or as protein coding. | |||
I'm '''confident this PTTG1IP-like gene is protein coding throughout Osteichthyes'''. So, I'd like your input on what it should be named (pituitary tumor-transforming gene 1 protein-interacting protein probably isn't appropriate). | |||
I'd appreciate it if the curators at MGI, RGD, and Ensembl could look at this PTTG1IP-like gene and confirm that it's protein coding. | I'd appreciate it if the curators at MGI, RGD, and Ensembl could look at this PTTG1IP-like gene and confirm that it's protein coding. | ||
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4.30.2020 HGNC, ZFIN, and NCBI agree that this gene should be called '''PTTG1IP2 and "PTTG1IP family member 2"'''. | 4.30.2020 HGNC, ZFIN, and NCBI agree that this gene should be called '''PTTG1IP2 and "PTTG1IP family member 2"'''. | ||
The following species can have their official symbol updated to PTTG1IP2: | The following gene/species can have their official symbol updated to PTTG1IP2: | ||
human (GeneID: 102723899) | human (GeneID: 102723899) | ||
mouse (MGI:2686532; GeneID: 381716) | mouse (MGI:2686532; GeneID: 381716) | ||
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X.tropicalis (XB-GENEPAGE-5751720; GeneID: 496874) | X.tropicalis (XB-GENEPAGE-5751720; GeneID: 496874) | ||
zebrafish (GeneID: 101886260) | zebrafish (GeneID: 101886260) | ||
15June 2020 | |||
Human symbol has changed for genepage ID: 5751720 From pttg1ip2 to LOC102723899, Xenopus name will remain unchanged, | |||
Revision as of 15:21, 7 July 2020
pttg1lp2
This is the community wiki page for the gene pttg1lp2 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase
nomenclature update
03.24.2020
Following discussion with HGNC and NCBI RefSeq, name change from and 'unnamed' PTTG1IP-like gene to "PTTG1IP family member 2", gene symbol "PTTG1IP2" in human. In Xenopus therefore, "PTTG1IP family member 2", gene symbol "pttg1lp2"
background to name change:reported by David Webbat NCBI refSeq.
Key: RSCOM-45 URL: https://ncbijira.ncbi.nlm.nih.gov/browse/RSCOM-45
Components: chicken, Ensembl, human, mouse, rat, vgnc, xenopus, zebrafish
Reporter: David Webb
Assignee: Elspeth Bruford
Hi HGNC, I'd like your input on a PTTG1IP-like gene that is inconsistently annotated and named.
The paralogous gene, PTTG1IP, is consistently found upstream of the SUMO3 gene in Osteichthyes and a PTTG1IP-like gene is consistently found upstream of the CDK14 gene in Osteichthyes.
However, in mammals this PTTG1IP-like gene is sometimes unannotated or is annotated as non-coding or as protein coding.
I'm confident this PTTG1IP-like gene is protein coding throughout Osteichthyes. So, I'd like your input on what it should be named (pituitary tumor-transforming gene 1 protein-interacting protein probably isn't appropriate).
I'd appreciate it if the curators at MGI, RGD, and Ensembl could look at this PTTG1IP-like gene and confirm that it's protein coding. -DW
Gene IDs effected:
human (GeneID: 102723899)
mouse (MGI:2686532; GeneID: 381716)
rat (RGD:9118001; GeneID: 103692048)
chicken (GeneID: 420545)
X.tropicalis (XB-GENEPAGE-5751720; GeneID: 496874)
zebrafish (GeneID: 101886260)
4.30.2020 HGNC, ZFIN, and NCBI agree that this gene should be called PTTG1IP2 and "PTTG1IP family member 2".
The following gene/species can have their official symbol updated to PTTG1IP2: human (GeneID: 102723899) mouse (MGI:2686532; GeneID: 381716) rat (RGD:9118001; GeneID: 103692048) chicken (GeneID: 420545) X.tropicalis (XB-GENEPAGE-5751720; GeneID: 496874) zebrafish (GeneID: 101886260)
15June 2020 Human symbol has changed for genepage ID: 5751720 From pttg1ip2 to LOC102723899, Xenopus name will remain unchanged,