XB-FEAT-5835883

acd

This is the community wiki page for the gene acd please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.

nomenclature changes

04/14/2023

Following orthology and synteny analysis, the gene name & symbol was changed from XB5835883 to adc, ACD shelterin complex subunit and telomerase recruitment factor.

Although synteny with mammals is not maintained, the gene is in a conserved gene patern in other amphibians.

Human/MOUSE/RAT: CTCF> CARMIL2> ACD< PARD6A> ENKD1<

compared with

Human chr6: TUBB2B< [ELEMENTS] LOC100422781 [ENHANCERS/SILENCER ELEMENTS, sharpr reg region 12113] PSMG4> SLC22A23<

Amphibians:

Xtropicalis Chr6: slc22a23> psmg4< XB5835883> bphl< tubb2b> serpinb4< serpinb11< ecl3<

Xlaevis Chr6.L: slc22a23.L> psmg4.L< XB5835883.L> bphl.L< tubb2b.L> serpinb4.L< ecl3.L<

Xlaevis Chr6.S: slc22a23.S> psmg4.S< XB5835883.S> tubb2b.S>

Nanorana parkeri: BPHL> ACD< PSMG4> SLC22A23<

gene identity is also strongly support by DIOPT analsyis, comparing protein to homology groups in DIOPT/EggNog.