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Synthetic retinoid. Retinoic acid receptor β (RARβ) agonist in vivo; RARα and RARγ antagonist in vitro. Inhibits breast cell proliferation by inducing active transforming growth factor β (TGFβ) and causes G1 arrest.
- Using frogs faces to dissect the mechanisms underlying human orofacial defects. Dickinson AJ. Semin Cell Dev Biol. March 1, 2016; 51 54-63.
- Median facial clefts in Xenopus laevis: roles of retinoic acid signaling and homeobox genes. Kennedy AE, Dickinson AJ. Dev Biol. May 1, 2012; 365 (1): 229-40.
- National Center for Biotechnology Information. PubChem Compound Database; CID=9875424,