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Colchicine is known as a mitotic inhibitor. It has been used to induce polyploidy in plants, but in amphibians has been used to induce digit loss and reduced number of digits in regenerating limbs.
see wikipedia entry for more details:https://en.wikipedia.org/wiki/Colchicine [[File:______|frame|right|_______ structure, photo from Sigma-Aldrich]]
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