Cycloheximide

Description

"Cycloheximide (CHX) is an antibiotic produced by S. griseus. Its main biological activity is translation inhibition in eukaryotes resulting in cell growth arrest and cell death. CHX is widely used for selection of CHX-resistant strains of yeast and fungi, controlled inhibition of protein synthesis for detection of short-lived proteins and super-induction of protein expression, and apoptosis induction or facilitation of apoptosis induction by death receptors."

• • -Sigma Description

Cycloheximide structure, photo from PubChem

Suppliers

• Sigma c7698
• Santa Cruz sc-3508
• Tocris 0970
• Enzo
• Abcam ab120093

References

• PubChem
• Germain et al., 2000
• Henningfeld et al., 2002
• Zhang et al., 2014
• Sible et al 1997
• Nishitani et al 2016
• Gere-Becker et al 2018

>1679 Xenbase articles contain a reference to cycloheximide according to textpresso

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