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"Cycloheximide (CHX) is an antibiotic produced by S. griseus. Its main biological activity is translation inhibition in eukaryotes resulting in cell growth arrest and cell death. CHX is widely used for selection of CHX-resistant strains of yeast and fungi, controlled inhibition of protein synthesis for detection of short-lived proteins and super-induction of protein expression, and apoptosis induction or facilitation of apoptosis induction by death receptors."

    • -Sigma Description
Cycloheximide structure, photo from PubChem


Usage Notes


>1679 Xenbase articles contain a reference to cycloheximide according to textpresso