Propylthiouracil

Description

Synonym: PTU

Inhibits metamorphosis via thyroid hormone signaling.

"5-Propyl-2-thiouracil (PTU) is used to induce and study mechanisms of hypothyroidism at the levels of thyroid hormone biosynthesis and gene regulation."

• -Sigma Product Description

propylthiouracil structure, photo from PubChem

Genes Affected

maybe THRA

Suppliers

• Sigma

References

• Pubchem
• MaClean et al., 1976

>69 Xenbase articles contain a reference to propylthiouracil according to textpresso

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