XB-FEAT-1003079

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mfhas1

This is the community wiki page for the gene mfhas1 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

nomenclature changes

06.16.2021

Human name has changed for Entrez Gene: 9258. From malignant fibrous histiocytoma amplified sequence 1 to multifunctional ROCO family signaling regulator 1


summary for human MFHAS1 from NCBI

dentified in a human 8p amplicon, this gene is a potential oncogene whose expression is enhanced in some malignant fibrous histiocytomas (MFH). The primary structure of its product includes an ATP/GTP-binding site, three leucine zipper domains, and a leucine-rich tandem repeat, which are structural or functional elements for interactions among proteins related to the cell cycle, and which suggest that overexpression might be oncogenic with respect to MFH. [provided by RefSeq, Jul 2008]