XB-FEAT-22063233

Note: there are two FMO5 orthologous genes in Xenopus, fmo5.1 and fmo5.2

nomenclature changes

05.13.19 Human name has changed for Entrez Gene: 2330. From flavin containing monooxygenase 5 to flavin containing dimethylaniline monoxygenase 5

Summary from NCBI for human FMO5

Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009]