XB-FEAT-29081974

plscr1l

This is the community wiki page for the gene plscr1l please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.

Summary for human PLSCR1 - phospholipid scramblase 1- from NCBI

This gene encodes a phospholipid scramblase family member. The encoded protein is involved in disruption of the asymmetrical distribution of phospholipids between the inner and outer leaflets of the plasma membrane, resulting in externalization of phosphatidylserine. This cell membrane disruption plays an important role in the blood coagulation cascade as well as macrophage clearing of apoptotic cells. The encoded protein has additionally been implicated in gene regulation and interferon-induced antiviral responses. [provided by RefSeq, May 2022]