XB-FEAT-29084950

tnfsf13

This is the Xenbase community wiki page for Xenopus tnfsf13 genes. Feel free to record here any information relevant to tnfsf13 that is not recored elsewhere on Xenbase.

nomenclature changes

11.22.2024 Xenopus symbol has changed for genepage ID: 29084950 From LOC101730941 to tnfsf13

summary from NCBi about human TNFSF13

The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Alternative splicing results in multiple transcript variants. Some transcripts that skip the last exon of the upstream gene (TNFSF12) and continue into the second exon of this gene have been identified; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq, Oct 2010]