XB-FEAT-478255

sostdc1

This is the community wiki page for the gene sostdc1 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.

summary from NCBI

This gene is a member of the sclerostin family and encodes an N-glycosylated, secreted protein with a C-terminal cystine knot-like domain. This protein functions as a bone morphogenetic protein (BMP) antagonist. Specifically, it directly associates with BMPs, prohibiting them from binding their receptors, thereby regulating BMP signaling during cellular proliferation, differentiation, and programmed cell death. [provided by RefSeq, Jul 2008]