XB-FEAT-483337

nfe2l3

This is the community wiki page for the gene nfe2l3 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

nomenclature changes

10.20.2021 Human name has changed for Entrez Gene: 9603. From nuclear factor, erythroid 2 like 3 to NFE2 like bZIP transcription factor 3

Human symbol unchanged : NFE2L3, although we expect it will be updated to remove the L for ‘like’

summary for human NFE2L3 from NCBI= This gene encodes a member of the cap 'n' collar basic-region leucine zipper family of transcription factors. The encoded protein heterodimerizes with small musculoaponeurotic fibrosarcoma factors to bind antioxidant response elements in target genes. This protein is a membrane bound glycoprotein that is targeted to the endoplasmic reticulum and the nuclear envelope. Pseudogenes of this gene are found on chromosomes 16, 17, and 18. [provided by RefSeq, Mar 2009]