XB-FEAT-492942

unc93b1

This is the community wiki page for the gene unc93b1 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

nomenclature changes

08/07/2017 Human name has changed for Entrez Gene: 81622. From unc-93 homolog B1 (C. elegans) to unc-93 homolog B1, TLR signaling regulator

summary from NCBI

This gene encodes a protein that is involved in innate and adaptive immune response by regulating toll-like receptor signaling. The encoded protein traffics nucleotide sensing toll-like receptors to the endolysosome from the endoplasmic reticulum. Deficiency of the encoded protein has been associated with herpes simplex encephalitis. [provided by RefSeq, Feb 2014]