XB-FEAT-5872576

acnat1

This is the community wiki page for the gene acnat1 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

nomenclature changes

undated:

Xenopus gene name/symbol changed from loc100488333, uncharatcterised to XB5872576 [provisional:acnat1]. provisional ortholog of acyl-coenzyme A amino acid N-acyltransferase 1

15MAY2023

name changed from XB5872576 [provisional:acnat1], provisional ortholog of acyl-coenzyme A amino acid N-acyltransferase 1 to acnat1(acnat1 .1), acyl-coenzyme A amino acid N-acyltransferase 1 gene 1

15MAY2023 gene symbol changes from XB5872576 to acnat1, I'm giving the XB5872576 alleles the acnat1 gene 1 designation, and will request new gene pages for the other duplicates. need a protein/sequence alignment and phyligeneitc assessemtn perhaps to decide if the other Xtropicalis genes are best called acnat1 or acnat2.

synteny patterns

Synteny between Xenopus and rodents indicates conserved flanking genes, but noteably an expansion of the acnat1 and acnat2 genes in X. tropicalis, and 3 X acnat1 genes in X. laevis.

Mouse/Rat, gene : Acnat1, acyl-coenzyme A amino acid N-acyltransferase 1

MouseChr4: Scnat2< Gm12451> Gm12452> Rbpj-ps2> Acnat1< Gm33009> Gm32894> Baat<

ratChr5: Acnat2< Scnat2-ps1< Acnat1< Baat< Mrp150<

Xtrop.Chr1: LOC108645719(spns1)> tspan36> baat< LOC100496940(acnat2)> LOC100497260(acnat2)> LOC100497580(acnat1)> LOC116408197(acnat2)> LOC100497423(acnat2)> LOC100497738(acnat2)> XB5872576(acnat1) mapk4< ska1< me2> elac1> smad4>

X.lavies.Chr1L: tspan36.L> LOC121393106(acnat1)> LOC108718574(acnat1 like)> XB5872576(acnat1)> ska1.L> mapk4.L>