XB-FEAT-6462715

abcc13

This is the gene page wiki for Xenopus abcc13. Feel free to record here, any details that are not recorded elsewhere on Xenbase.

nomenclature changes

3/4/2022 remove pseudogene from gene name, as all non-human orthologs are thought to be functional protein coding genes.

summary from NCBI for Human

This gene is a member of the superfamily of genes encoding ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This family member is part of the MRP subfamily, which is involved in multi-drug resistance, but the human locus is now thought to be a pseudogene incapable of encoding a functional ABC protein. Alternative splicing results in multiple transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008]