XB-FEAT-940202

f2rl3

This is the community wiki page for the gene f2rl3 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

summary

This gene encodes a member of the protease-activated receptor subfamily, part of the G-protein coupled receptor 1 family of proteins. The encoded receptor is proteolytically processed to reveal an extracellular N-terminal tethered ligand that binds to and activates the receptor. This receptor plays a role in blood coagulation, inflammation and response to pain. Hypomethylation at this gene may be associated with lung cancer in human patients. [provided by RefSeq, Sep 2016]

nomenclature changes

undated Human name has changed for Entrez Gene: 9002. From coagulation factor II (thrombin) receptor-like 3 to F2R like thrombin/trypsin receptor 3

06/05/2017 Human name has changed for Entrez Gene: 9002. From F2R like thrombin/trypsin receptor 3 to F2R like thrombin or trypsin receptor 3