XB-FEAT-955496

bltp2

This is the community wiki page for the gene bltp2 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

-summary for human BLTP2 from NCBI= This gene was initially characterized in human as having high expression levels in breast carcinomas and breast cancer cell lines. This gene also has increased expression in prostrate cancer cells relative to normal prostrate tissues. Expression of this gene is negatively regulated by direct binding of the microRNA miR-195 to its 3' UTR. miR-195 has been shown to modulate the invasiveness of prostrate cancer cells and xenograft metastases by downgrading expression of this gene. In mouse, the protein encoded by this gene was identified as an antigen on acute monocytic leukemia cells. In human, alternative splicing results in multiple transcript variants encoding distinct isoforms; some of these isoforms are predicted to contain an RNA pol II promoter FMP27 protein domain and a Golgi-body-localization APT1 domain. [provided by RefSeq, Apr 2017]

nomenclature changes

17JULY2022

Human symbol has changed for genepage ID: 955496 From KIAA0100 to BLTP2

Xenopus symbol has changed for genepage ID: 955496 From kiaa0100 to bltp2

Xenopus and Human name has changed for genepage ID: 955496 from KIAA0100 to bridge-like lipid transfer protein family member 2