XB-FEAT-961829

tmem128l

This is the community wiki page for the gene tmem128l please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

synteny and orthology

there are 2 tmem128 genes in Xenopus: tmem128 (XB-GENEPAGE-974140) and tmem128l (XB-GENEPAGE-961829)

synteny supports Xenopus tmem128 as the true ortholog of the human TMEM128 gene.

Xtr: Chr1: nsg1< ... zbtb49< ... lyar> ... tmem128> ... otop1> ... otop1.2>

human: chr4: OR7E43P< ... OTOP1< ... TMEM128< ... LOC112939936> ... LYAR<

X. tropicalis tmem128l is also on Chr 1 but is flanked but toll-like receptors 1 and 6. (we can't find a candidate gene in X. laevis)

Human LOC124900695 may be the ortholog of tmem128l, or not. needs protein alignment to determine. Synteny also suggests Xenopus LOC105945522 may be ortholog of TMEM156 or LOC105374418(unch) (and would follow the human name).

Xtrop CHR1: kif3> ... LOC101733197(inpp5e)> ... tmem128l< ... tlr1>... tlr6> ... LOC100495326< .. fam114a1> ... LOC105945522[unch)< ... klhl5> ...

human chr4: TLR10< ...LOC112939933(sharpr/13104)> ... LOC124900695(unch)< ... TLR1< ...TLR6< ...FAM114A1> .... TMEM156< ... LOC105374418(unch)< ... KLHL5> ... LOC112939934(SHAPR-MPRA)