XB-FEAT-971749

cyp3a4

This is the community wiki page for the gene cyp3a4 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

synteny

The ‘cyp3a4’ genes are duplicated on Chromosome 5/5L in the X. tropicalis and X. laevis.L subgenome. They are missing from/not present in the X.laevis.S subgenome.

The synteny is conserved as follows:

Xtrop. Chr5: cyb5r4 ... x ... cyp3a4.2 ... cyp3a4 ... ripply2.2 ... ripply2.1 ... snap91

XlaChr5L: cyb5r4.L... LOC#3092(anothercypreg.region) ... cyp3a4.2.L ... LoC#3716(tmpo) ... cyp3a4.L ... Loc#16888(dram1) ... ripply2.2.L ... ripply2.1.L ... snap91.L

Xla.Chr5S: cyb5r4.S … x … x … x… x … x … ripply2.2 ... ripply2.1 ... snap91

Human chr7:CYP3A7… CYP3AP2 … CYP3A4 … CYP3A4(5’reg.region) [ enhancers] CYP3A137P …CYP3A43 …

nomenclature changes

09/20/2024

Xenopus gene symbol changed from cyp3a4.1 to cyp3a4