XB-FEAT-983251

pals2

This is the community wiki page for the gene pals2 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.

summary for human PALS2 from NCBI

Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like (see DLG1; MIM 601014), ZO1-like (see TJP1; MIM 601009), p55-like (see MPP1; MIM 305360), and LIN2-like (see CASK; MIM 300172), based on their size and the presence of additional domains. MPP6 [PALS2] is a member of the p55-like MAGUK subfamily (Tseng et al., 2001 [PubMed 11311936]).[supplied by OMIM, Mar 2008]

nomenclature changes

03.17.2021

Human symbol has changed for genepage ID: 983251 From MPP6 to PALS2

Xenopus symbol has changed for genepage ID: 983251 From mpp6 to pals2

Human symbol has changed for Entrez Gene: 51678. From MPP6 to PALS2

Human name has changed for Entrez Gene: 51678. From membrane palmitoylated protein 6 to protein associated with LIN7 2, MAGUK family member

10.20.2021

Human name has changed for Entrez Gene: 51678. From protein associated with LIN7 2, MAGUK family member to protein associated with LIN7 2, MAGUK p55 family member