XB-FEAT-988038

b4galt3l1

This is the community wiki page for the gene b4galt3l1 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

nomenclature changes

04/06/2020

Human symbol has changed for genepage ID: 988038 From b4galt3l1 to b4galt3

Named changed from UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 like 1 to beta-1,4-galactosyltransferase 3

08/20/2020

The previous name change was incorrect, and this XB-GENEPAGE-988038 should be named b4galt3l1/beta-1,4-galactosyltransferase 3-like 1 rather than b4galt3. The name has reverted to b4galt3l beta-1,4-galactosyltransferase 3-like 1

notes on synteny/orthologs

from David Webb at NCBI/ RefSeq

The b4galt3l1 gene appears to have been lost in mammals (therefore no ortholog links to human rat or mouse) though it goes back at least as far as gnathostomes where it consistently resides between the B4GALT4 and ARHGAP31 genes (it's also missing or moved in some teleosts like D. rerio but it's there in reedfish and spotted gar).

In amphibians, reptiles and birds there's often another gene between B4GALT4 and ARHGAP31 which Xenbase correctly identifies as b3gat1l (XB-GENEPAGE-5956385; GeneID: 594896).

synteny notes: archelosaurs, amphibians TEX55>...UPK1B>...ARHGAP31<...B3GATL>...B4GALT3L>...B4GALT4<...TMEM39A>...FAAHL<...CHD1L>

squamates TEX55>...UPK1B>...ARHGAP31<...B3GATL>...B4GALT3L>...B4GALT4< ...SMAD9>...RFXAP<

mammals TEX55>...UPK1B>...B4GALT4<...ARHGAP31>...TMEM39A<

gar UPK1B>...ARHGAP31<...B3GATL>...B4GALT3L>...B4GALT4< ...TAF13<...CASR

reedfish TEX55>...UPK1B>...ARHGAP31<...B4GALT3L>...B4GALT4< ...MTMR2>

teleosts TEX55> ...ARHGAP31<...B4GALT4< ...CASR< *I don't think B3GATL and B4GALT3L moved elsewhere.

chondrichthyes TEX55>...UPK1B>...ARHGAP31<...B3GATL>...B4GALT4>...DRD3> *B4GALT3L may have moved between NOX4 and FOLH1B