XB-FEAT-990957

dlec1

This is the community wiki page for the gene dlec1 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

summary from NCBI

In humans, the cytogenetic location of this gene is 3p21.3, and it is located in a region that is commonly deleted in a variety of malignancies. Down-regulation of this gene has been observed in several human cancers including lung, esophageal, renal tumors, and head and neck squamous cell carcinoma. In some cases, reduced expression of this gene in tumor cells is a result of aberrant promoter methylation. Several alternatively spliced transcripts have been observed that contain disrupted coding regions and likely encode nonfunctional proteins.[provided by RefSeq, Mar 2016]

nomenclature issues

05.14.2018 Human name has changed for Entrez Gene: 9940. From deleted in lung and esophageal cancer 1 to DLEC1, cilia and flagella associated protein