XB-FEAT-991452

clpx

This is the community wiki page for the gene clpx please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.

nomenclature changes

10.18.2019 Human name has changed for Entrez Gene: 10845. From caseinolytic mitochondrial matrix peptidase chaperone subunit to caseinolytic mitochondrial matrix peptidase chaperone subunit X

Summary for human CLPX from NCBI

The protein encoded by this gene is part of a protease found in mitochondria. This protease is ATP-dependent and targets specific proteins for degradation. The protease consists of two heptameric rings of the CLPP catalytic subunit sandwiched between two hexameric rings of the chaperone subunit encoded by this gene. Targeted proteins are unwound by this protein and then passed on to the CLPP subunit for degradation. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Nov 2015]