Small Molecules for Xenopus Research
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Important small molecule references
- Database of Small Molecules by Feldman and Hogue 2006 at PubChem
- Wnt/Notch by Myers and Krieg 2014
- Ubiquitin-proteasome by Salic and King 2005
Alphabetical List of Small Molecules With Literature References
- 11-cis retinal
- 18alpha-glycyrretinic acid
- 3,3,5-triiodothyronine (T3)
- 5HT (seratonin)
- activin
- AG1296
- AG1879
- AGN193109
- alpha-amanitin
- anandamide
- apelin
- aphidicolin
- AZD1480
- BAPTA-AM
- beta-xyloside
- bumetanide
- calcium ionophore
- CGP54626
- Chelerythrine
- chymostatin
- Colcemide
- concanamycin
- cycloheximide
- cyclopamine
- Cyclosporin A
- Cytochalasin B
- cytochalasin D
- Demecolcine
- deltamethrin
- dexamethosone
- DHT(dihydrotestosterone)
- diazepam
- Ex-527
- forskolin
- fusicoccin
- gentamycin
- GM6001
- heptanol
- herbimycin A
- IBMX
- jasplakinolide
- KT 5720
- lansoprazole
- LiCl
- Mg132
- MMP-2 inhibitor II
- nicorandil
- nifedipine
- nocodazole
- NSC-87877
- o-phenanthroline
- okadaic acid
- olomoucine
- ouabain
- p-MPPI
- Paclitaxel
- phaclofen
- PMA
- PP2
- primaquine
- propylthiouracil
- quinpirole
- rapamycin
- retinoic acid
- RS67333
- RU486
- SB 203580
- sodium nitroprusside
- SP600125
- SU5402
- SU6656
- Suramin
- tautomycin
- taxol
- thyroxine (T4)
- TTNPB
- tunicamycin
- Y27632
- ZM 447439
The Following are in need of standardization and curation
- cytochalasin D
- latrunculin B
- colchicine
- AP1510
- U0126
- MS222
- SB-431542
- Nu6102
- purmorphamine
- TG003
- SB505124
- U73122
- R(+)BayK 8644
- nicardipine
- etoposide
- Pyrazoleanthrone
List of Molecules Affecting Specific Pathways
cAMP
CDK/Cyclins
ERK/MAPK
JAK/STAT
JNK
Nitric Oxide
PDGF
Retinoic Acid
Shh
TGF-beta/BMP
Wnt
Epigenetics
Protease Inhibitors
- chymostatin
- GM6001 (MMP inhibitor)
- o-phenanthroline(MMP inhibitor)
- BB-94 MMP inhibitor
- GI254023X MMP10 inhibitor
Small Molecules by Biological Function
Angiogenesis
Apoptosis
Autophagy
Calcium Signaling
Circadian Rhythm
Cytoskeletal Inhibitors
- Cytochalasin B
- cytochalasin D
- Colcemide
- jasplakinolide is an activator
- taxol
- Paclitaxel
Cell Cycle, including mitosis
DNA Damage/Repair
Growth Cone, Filopodia, and other Cytoskeletal projections
- PP2
- SU6656
- cytochalasin D 0.1 uM Sigma
- latrunculin B 30nM Sigma
- colchicine 12.5uM Sigma
- nocodazole 0.1uM Sigma
Hatching
Metamorphosis
Neurotransmission
Protein Recycling
Drugs by Gene Class
Channels, including ATPases
G Protein Receptors
Kinases
Phosphatases
Small GTPases
Protein Synthesis
- anisomycin 40uM Sigma
- cycloheximide 40uM