Small Molecules for Xenopus Research: Difference between revisions
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===Thyroid Signaling=== | ===Thyroid Signaling=== | ||
*[[NH-3]] | |||
Description | Description | ||
Revision as of 08:13, 16 May 2023
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Important small molecule references
- Database of Small Molecules by Feldman and Hogue 2006 at PubChem
- Wnt/Notch by Myers and Krieg 2014
- Ubiquitin-proteasome by Salic and King 2005
Alphabetical List of Small Molecules With Literature References
- 1,3-Dicyclohexylurea
- 11-cis retinal
- 18alpha-glycyrrhetinic acid
- 2'-deoxyadenosine
- 2-APB
- 2-Deoxyglucose
- 3,3,5-triiodothyronine (T3)
- 5HT (seratonin)
- 8-Pcpt-2-O-Me-cAMP-AM
- activin
- Adenosine, periodate oxidized
- AG1296
- AG1879
- AGN193109
- alpha-amanitin
- Alisertib
- anandamide
- AP-III-a4
- apelin
- aphidicolin
- Aroclor 1254
- Atrazine
- AZD1480
- Bafilomycin A1
- BAPTA-AM
- Barasertib
- Benzaldehyde, 3-allyl-2-(2-(diethylamino)ethoxy)-(DEAB)
- beta-xyloside
- blebbistatin
- BMS-453
- Brefeldin A (BFA)
- bumetanide
- calcium ionophore
- canertinib
- CGP54626
- Chelerythrine
- chenodeoxycholic acid
- chlorpromazine
- chymostatin
- Citral
- Colcemide
- concanamycin
- CP-91149
- cycloheximide
- cyclopamine
- Cyclosporin A
- Cytochalasin B
- cytochalasin D
- D-AP5
- D-NAME
- deltamethrin
- dexamethosone
- DHT(dihydrotestosterone)
- diazepam
- Difopein
- Diphenyleneiodonium Chloride
- DMH-1
- Dorsomorphin
- DRB
- Ex-527
- finasteride
- folic acid
- forskolin
- fusicoccin
- gallein
- GANT 61
- gentamycin
- GSK3-inhibitor IX (BIO)
- GM6001
- H-89 Dihydrochloride
- heptanol
- herbimycin A
- Hh-Ag1.8
- Hydroxyurea
- IBMX
- Iodoacetic acid
- jasplakinolide
- 6-B345TTQ
- Ketamine
- KT 5720
- L-NAME
- lansoprazole
- latrunculin A
- latrunculin B
- LDN-193189
- Leflunomide
- leucovorin
- LiCl
- Lovastatin
- LY294002
- m-3M3FBS
- methotrexate (MTX)
- metronidazole
- Mg132
- MK-2206
- MMP-2 inhibitor II
- MS-275
- Mubritinib
- nicorandil
- Nicotinamide
- Nicotinic acid
- nifedipine
- nocodazole
- NSC-87877
- o-phenanthroline
- okadaic acid
- olomoucine
- ouabain
- Olygomycin
- PD173074
- PD-407824
- p-MPPI
- Paclitaxel
- phaclofen
- phenylthiourea (PTU)
- Picropodophyllin
- PMA
- PP2
- primaquine
- Progesterone
- propylthiouracil
- psoralen
- pyrimethamine
- quinpirole
- rac1 inhibitor
- rapamycin
- retinoic acid
- Retinol
- RO-3306
- RS67333
- RU486
- SAHA
- SB 203580
- SB431542
- SB-505124
- SCH28080
- SNAP
- sodium nitroprusside
- sodium perchlorate
- SP600125
- SU5402
- SU6656
- Suramin
- tautomycin
- taxol
- thyroxine (T4)
- Torin 2
- Trichostatin A
- trimetrexate
- Triptolide
- TTNPB
- Tubercidin
- tunicamycin
- Tyrphostin AG 1478
- U73122
- Y27632
- ZM 447439
The Following are in need of standardization and curation
- AM251
- AM281
- AP1510
- AR-A014418
- BHQ
- b-aminoproprionitrile
- beclomethasone
- Butyrate
- calcicludine
- Calyculin A
- celastrol
- celecoxib
- chromanol 293B
- chlorate
- cytochalasin D
- colchicine
- dimethyloxallyl glycine (DMOG)
- diclofenac
- etoposide
- IWR1
- GW843682X
- leptomycin B
- LY320135
- methylcellulose (MC)
- methimazole
- MBCD or MBetaCD
- MS222
- nicardipine
- Nu6102
- purmorphamine
- Pyrazoleanthrone
- R(+)BayK 8644
- RHC80267
- RL-3
- SAG
- SB-431542
- TG003
- Thapsigargin
- U0126
- ursodeoxycholic acid
- valproic acid (VPA)
- Echinomycin
- Gö 6983
- phenylhydrazine
- ω-conotoxin–GVIA
- flunarizine
- tetrodotoxin
- veratridine
- NBI-27914
Small Molecules Affecting Pathways
cAMP
CDK/Cyclins
ERK/MAPK
Folic Acid
JAK/STAT
JNK
Nitric Oxide
PDGF
Retinoic Acid
Shh
TGF-beta/BMP
Thyroid Signaling
Description
NH-3 is an orally active, reversible thyroid hormone receptor (THR) antagonist with an IC50 of 55 nM. NH-3, a derivative of the selective thyromi-metic GC-1, inhibits binding of thyroid hormones to their receptor and that inhibits cofactor recruitment.
formula
C28H27NO6 Synonyms[edit]
=Suppliers=[edit]
=Usage Notes=[edit]
=References= [edit] PubMed ID: 37083105 https://pubmed.ncbi.nlm.nih.gov/37083105/
Wnt
Epigenetics
Protease Inhibitors
- chymostatin
- GM6001 (MMP inhibitor)
- o-phenanthroline(MMP inhibitor)
- BB-94 MMP inhibitor
- GI254023X MMP10 inhibitor
Small Molecules affecting Biological Functions & Processes
Angiogenesis
Apoptosis
Autophagy
Calcium Signaling
Circadian Rhythm
Cytoskeletal Inhibitors
- Cytochalasin B
- cytochalasin D
- Colcemide
- Colchicine
- jasplakinolide is an activator
- latrunculin B
- taxol
- Paclitaxel
Cell Cycle, including mitosis
Cell migration, including specific cell lineage removal
Cilia
DNA Damage/Repair
DNA Synthesis
DNA mutagenic compounds
- ENU or N-nitroso-N-ethylurea 100mM Sigma N3385
Growth Cone, Filopodia, and other Cytoskeletal projections
- PP2
- SU6656
- cytochalasin D 0.1 uM Sigma
- latrunculin B 30nM Sigma
- colchicine 12.5uM Sigma
- nocodazole 0.1uM Sigma
- RHC80267
Hatching
Left-Right Patterning
Metamorphosis
Neurotransmission
Protein Recycling
Drugs by Gene Class
Channels, including ATPases
G Protein Receptors
Kinases
Phosphatases
Small GTPases
Protein Synthesis
- anisomycin 40uM Sigma
- cycloheximide 40uM
Retinoids
- TTNPB Sigma
Textpresso Small Molecules to Research
- importazole inhibits importin
- M119
- GBG or GBetaGamma or G Protein Beta Gamma
- LY-294002 inhibits PI3K and autophagy